Markers for hypersensitive response and senescence show distinct patterns of expression

Dominique Pontier, Susheng Gan, Richard M. Amasino, Dominique Roby, Eric Lam

Research output: Contribution to journalArticle

151 Citations (Scopus)

Abstract

Controlled cellular suicide is an important process that can be observed in various organs during plant development. From the generation of proper sexual organs in monoecious plants to the hypersensitive response (HR) that occurs during incompatible pathogen interactions, programmed cell death (PCD) can be readily observed. Although several biochemical and morphological parameters have been described for various types of cell death in plants, the relationships existing between those different types of PCD events remain unclear. In this work, we set out to examine if two early molecular markers of HR cell death (HIN1 and HSR203J) as well as a senescence marker (SAG12) are coordinately induced during these processes. Our result indicates that although there is evidence of some cross-talk between both cell death pathways, spatial and temporal characteristics of activation for these markers during hypersensitive response and senescence are distinct. These observations indicate that these markers are relatively specific for different cell death programs. Interestingly, they also revealed that a senescence-like process seems to be triggered at the periphery of the HR necrotic lesion. This suggests that cells committed to die during the HR might release a signal able to induce senescence in the neighboring cells. This phenomenon could correspond to the establishment of a second barrier against pathogens. Lastly, we used those cell death markers to better characterize cell death induced by copper and we showed that this abiotic induced cell death presents similarities with HR cell death.

Original languageEnglish (US)
Pages (from-to)1243-1255
Number of pages13
JournalPlant Molecular Biology
Volume39
Issue number6
DOIs
StatePublished - Apr 1 1999

Fingerprint

hypersensitive response
cell death
Cell Death
apoptosis
Plant Organogenesis
suicide
lesions (plant)
pathogens
plant organs
plant development
copper
Suicide
Copper
genetic markers

All Science Journal Classification (ASJC) codes

  • Agronomy and Crop Science
  • Genetics
  • Plant Science

Keywords

  • Hypersensitive response
  • Programmed cell death
  • Senescence
  • Tobacco mosaic virus

Cite this

Pontier, Dominique ; Gan, Susheng ; Amasino, Richard M. ; Roby, Dominique ; Lam, Eric. / Markers for hypersensitive response and senescence show distinct patterns of expression. In: Plant Molecular Biology. 1999 ; Vol. 39, No. 6. pp. 1243-1255.
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Markers for hypersensitive response and senescence show distinct patterns of expression. / Pontier, Dominique; Gan, Susheng; Amasino, Richard M.; Roby, Dominique; Lam, Eric.

In: Plant Molecular Biology, Vol. 39, No. 6, 01.04.1999, p. 1243-1255.

Research output: Contribution to journalArticle

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AU - Gan, Susheng

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