TY - JOUR
T1 - Maternal lifestyle characteristics during pregnancy, and the risk of obesity in the offspring
T2 - A study of 5,125 children
AU - Mourtakos, Stamatis P.
AU - Tambalis, Konstantinos D.
AU - Panagiotakos, Demosthenes B.
AU - Antonogeorgos, George
AU - Arnaoutis, Giannis
AU - Karteroliotis, Konstantinos
AU - Sidossis, Labros S.
N1 - Funding Information:
The authors want to thank the study subjects for their willingness to participate. We are also very grateful to Mrs Chrysoula Alexi, Stavroula Parastatidou and Klairi Georgelli for their assistance with the data collection. This study was conducted with the support of the Institute for Translational Sciences at the University of Texas Medical Branch, supported in part by a Clinical and Translational Science Award (UL1TR000071) from the National Center for Advancing Translational Sciences, National Institutes of Health, OPAP SA – Greece, and support from the Harokopeio University Post Graduate program on Nutrition and Dietetics.
Publisher Copyright:
© Mourtakos et al.; licensee BioMed Central.
PY - 2015/3/21
Y1 - 2015/3/21
N2 - Background: To investigate the association between gestational weight gain, maternal age and lifestyle habits (e.g., physical activity, smoking, and alcohol consumption) during pregnancy, with Body Mass Index of the offspring at the age of 8. Methods: Α random sample of 5,125 children was extracted from a national database and matched with their mothers. With the use of a standardised questionnaire, telephone interviews were carried out for the collection of information like: maternal age at pregnancy, gestational weight gain (GWG), exercise levels, smoking and alcohol consumption. The Body Mass Index (BMI) status of the offspring at the age of 8 was calculated from data retrieved from the national database (e.g., height and weight). Results: The odds for being overweight/obese at the age of 8 for 1kg GWG, for smoking, and for mild exercise during pregnancy compared to sedentary was 1.01 (95%CI: 1.00, 1.02), 1.23 (95%CI: 1.03, 1.47) and 0.77 (95%CI: 0.65, 0.91), respectively. Further analysis revealed that offspring of women who exceeded the Institute of Medicine (IOM) maternal weight gain recommendations were at an increased risk of obesity (OR: 1.45; 95%CI, 1.26, 1.67) compared with offspring of women with GWG within the recommended range. Maternal age and alcohol consumption were not associated with the outcome (p>0.05). Conclusion: GWG, physical activity and smoking status during pregnancy were significantly associated with obesity for the offspring at the age of 8. Health care professionals should strongly advise women to not smoke and to perform moderate exercise during pregnancy to prevent obesity in the offspring in later life.
AB - Background: To investigate the association between gestational weight gain, maternal age and lifestyle habits (e.g., physical activity, smoking, and alcohol consumption) during pregnancy, with Body Mass Index of the offspring at the age of 8. Methods: Α random sample of 5,125 children was extracted from a national database and matched with their mothers. With the use of a standardised questionnaire, telephone interviews were carried out for the collection of information like: maternal age at pregnancy, gestational weight gain (GWG), exercise levels, smoking and alcohol consumption. The Body Mass Index (BMI) status of the offspring at the age of 8 was calculated from data retrieved from the national database (e.g., height and weight). Results: The odds for being overweight/obese at the age of 8 for 1kg GWG, for smoking, and for mild exercise during pregnancy compared to sedentary was 1.01 (95%CI: 1.00, 1.02), 1.23 (95%CI: 1.03, 1.47) and 0.77 (95%CI: 0.65, 0.91), respectively. Further analysis revealed that offspring of women who exceeded the Institute of Medicine (IOM) maternal weight gain recommendations were at an increased risk of obesity (OR: 1.45; 95%CI, 1.26, 1.67) compared with offspring of women with GWG within the recommended range. Maternal age and alcohol consumption were not associated with the outcome (p>0.05). Conclusion: GWG, physical activity and smoking status during pregnancy were significantly associated with obesity for the offspring at the age of 8. Health care professionals should strongly advise women to not smoke and to perform moderate exercise during pregnancy to prevent obesity in the offspring in later life.
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U2 - 10.1186/s12884-015-0498-z
DO - 10.1186/s12884-015-0498-z
M3 - Article
C2 - 25885759
AN - SCOPUS:84925293507
SN - 1471-2393
VL - 15
JO - BMC Pregnancy and Childbirth
JF - BMC Pregnancy and Childbirth
IS - 1
M1 - 66
ER -