Mechanical properties of septal cartilage homografts

Mark J. Glasgold, Y. Pedro Kato, David Christiansen, Joy A. Hauge, Alvin I. Glasgold, Frederick H. Silver

Research output: Contribution to journalArticle

24 Citations (Scopus)

Abstract

The compressive mechanical properties of untreated and chemically and physically treated nasal septum homografts were determined. Mechanical properties of control, saline-, thimerosal (Merthiolate)- and Alcide-treated specimens were similar. At high strains, the stiffness of treated cartilage ranged from 12.8 to 22.5 MPa and was unaffected by storage time. In comparison, irradiated and freeze-dried nasal septum exhibited stiffnesses of 35 and 37.5 MPa, respectively, after approximately 1 month of storage. These values of stiffness were significantly different from controls at a 0.95 confidence level. On the basis of these results, it was concluded that Alcide and Merthiolate treatment did not alter the compressive mechanical properties of cartilage and that a combination of these treatments may adequately sterilize and preserve nasal septum homografts.

Original languageEnglish (US)
Pages (from-to)374-379
Number of pages6
JournalOtolaryngology–Head and Neck Surgery
Volume99
Issue number4
DOIs
StatePublished - Oct 1988

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Thimerosal
Nasal Septum
Cartilage
Allografts
chlorine dioxide

All Science Journal Classification (ASJC) codes

  • Surgery
  • Otorhinolaryngology

Cite this

Glasgold, M. J., Kato, Y. P., Christiansen, D., Hauge, J. A., Glasgold, A. I., & Silver, F. H. (1988). Mechanical properties of septal cartilage homografts. Otolaryngology–Head and Neck Surgery, 99(4), 374-379. https://doi.org/10.1177/019459988809900404
Glasgold, Mark J. ; Kato, Y. Pedro ; Christiansen, David ; Hauge, Joy A. ; Glasgold, Alvin I. ; Silver, Frederick H. / Mechanical properties of septal cartilage homografts. In: Otolaryngology–Head and Neck Surgery. 1988 ; Vol. 99, No. 4. pp. 374-379.
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Glasgold, MJ, Kato, YP, Christiansen, D, Hauge, JA, Glasgold, AI & Silver, FH 1988, 'Mechanical properties of septal cartilage homografts', Otolaryngology–Head and Neck Surgery, vol. 99, no. 4, pp. 374-379. https://doi.org/10.1177/019459988809900404

Mechanical properties of septal cartilage homografts. / Glasgold, Mark J.; Kato, Y. Pedro; Christiansen, David; Hauge, Joy A.; Glasgold, Alvin I.; Silver, Frederick H.

In: Otolaryngology–Head and Neck Surgery, Vol. 99, No. 4, 10.1988, p. 374-379.

Research output: Contribution to journalArticle

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