Mechanical properties of septal cartilage homografts

Mark J. Glasgold, Y. Pedro Kato, David Christiansen, Joy A. Hauge, Alvin I. Glasgold, Frederick H. Silver

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The compressive mechanical properties of untreated and chemically and physically treated nasal septum homografts were determined. Mechanical properties of control, saline-, thimerosal (Merthiolate)- and Alcide-treated specimens were similar. At high strains, the stiffness of treated cartilage ranged from 12.8 to 22.5 MPa and was unaffected by storage time. In comparison, irradiated and freeze-dried nasal septum exhibited stiffnesses of 35 and 37.5 MPa, respectively, after approximately 1 month of storage. These values of stiffness were significantly different from controls at a 0.95 confidence level. On the basis of these results, it was concluded that Alcide and Merthiolate treatment did not alter the compressive mechanical properties of cartilage and that a combination of these treatments may adequately sterilize and preserve nasal septum homografts.

Original languageEnglish (US)
Pages (from-to)374-379
Number of pages6
JournalOtolaryngology–Head and Neck Surgery
Issue number4
StatePublished - Oct 1988

All Science Journal Classification (ASJC) codes

  • Surgery
  • Otorhinolaryngology

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    Glasgold, M. J., Kato, Y. P., Christiansen, D., Hauge, J. A., Glasgold, A. I., & Silver, F. H. (1988). Mechanical properties of septal cartilage homografts. Otolaryngology–Head and Neck Surgery, 99(4), 374-379.