Melanoma within the Seborrheic Keratosis

Isabelle Thomas, Nadia I. Kihiczak, Jerry Rothenberg, Shahida Ahmed, Robert A. Schwartz

Research output: Contribution to journalArticlepeer-review

14 Scopus citations


Seborrheic keratoses (SKs) are common benign nonmelanocytic epidermal tumors with characteristic clinical features, which are thought to allow a straightforward diagnosis in most situations. As a result, it is an accepted practice to destroy them without histopathologic confirmation. However, systematic reviews of histologic specimens reveal an erroneous clinical diagnosis or associated malignant tumors in a number of cases, including malignant melanomas. We describe a patient with a clinically typical-appearing SK, which was biopsied and histologically proven to be a malignant melanoma arising in the SK. Our report is a reminder that the reliability of clinical diagnosis of SKs needs to be questioned. In addition, a biopsy of SKs is not only warranted but necessary in order to identify a malignant melanoma that would otherwise be misdiagnosed or even completely missed.

Original languageEnglish (US)
Pages (from-to)559-561
Number of pages3
JournalDermatologic Surgery
Issue number4 I
StatePublished - Apr 1 2004

All Science Journal Classification (ASJC) codes

  • Surgery
  • Dermatology

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