TY - JOUR
T1 - Mental Work Demands and Late-Life Cognitive Impairment
T2 - Results From the Shanghai Aging Study
AU - Liang, Xiaoniu
AU - Chen, Zhao
AU - Dong, Xinqi
AU - Zhao, Qianhua
AU - Guo, Qihao
AU - Zheng, Li
AU - Deng, Wei
AU - Luo, Jianfeng
AU - Ding, Ding
N1 - Funding Information:
The authors thank all the neurologists, coordinators, research nurses, and technicians for their hard field work and all participants for their cooperation. The authors disclosed receipt of the following financial support for the research, authorship, and/or publication of this article: This project was funded by Shanghai Brain-Intelligence Project from STCSM [grant number 16JC1420500], Scientific Research Project from STCSM [grant number 17411950701, 17411950106], Natural Science Foundation and Major Basic Research Program of Shanghai [grant number 16JC1420100], and National Natural Science Foundation of China [grant number 81773513].
Funding Information:
The authors disclosed receipt of the following financial support for the research, authorship, and/or publication of this article: This project was funded by Shanghai Brain-Intelligence Project from STCSM [grant number 16JC1420500], Scientific Research Project from STCSM [grant number 17411950701, 17411950106], Natural Science Foundation and Major Basic Research Program of Shanghai [grant number 16JC1420100], and National Natural Science Foundation of China [grant number 81773513].
Publisher Copyright:
© The Author(s) 2018.
PY - 2019/6/1
Y1 - 2019/6/1
N2 - Objective: The aim of this study is to explore the association between mental work demands (MWDs) and late-life cognition among Chinese older adults. Method: Data were drawn from the baseline of the Shanghai Aging Study. Results: Among 3,546 participants, the mean MWDs index of participants with dementia, mild cognitive impairment (MCI), and cognitive normal were 2.8 (SD = 0.5), 2.8 (SD = 0.5), and 2.9 (SD = 0.4), respectively. Mini Mental State Examination (MMSE) scores in group with low MWDs level decreased more dramatically by increasing age than that in groups with middle and high MWDs level (p <.001). In a subgroup of participants with education ≥6 years, we found a positive correlation between MWDs index and MMSE score after adjusting for gender, age, body mass index, income, living alone, smoking, drinking, anxiety, depression, heart disease, hypertension, diabetes, and APOE-ε4 (apolipoprotein), by generalized linear model analysis (p <.001). Discussion: Our results suggest that long-time mental work stimulation during adulthood would have potential benefits to late-life cognition.
AB - Objective: The aim of this study is to explore the association between mental work demands (MWDs) and late-life cognition among Chinese older adults. Method: Data were drawn from the baseline of the Shanghai Aging Study. Results: Among 3,546 participants, the mean MWDs index of participants with dementia, mild cognitive impairment (MCI), and cognitive normal were 2.8 (SD = 0.5), 2.8 (SD = 0.5), and 2.9 (SD = 0.4), respectively. Mini Mental State Examination (MMSE) scores in group with low MWDs level decreased more dramatically by increasing age than that in groups with middle and high MWDs level (p <.001). In a subgroup of participants with education ≥6 years, we found a positive correlation between MWDs index and MMSE score after adjusting for gender, age, body mass index, income, living alone, smoking, drinking, anxiety, depression, heart disease, hypertension, diabetes, and APOE-ε4 (apolipoprotein), by generalized linear model analysis (p <.001). Discussion: Our results suggest that long-time mental work stimulation during adulthood would have potential benefits to late-life cognition.
KW - cognitive function
KW - community-based study
KW - dementia
KW - mental work demands
KW - mild cognitive impairment
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U2 - 10.1177/0898264318765034
DO - 10.1177/0898264318765034
M3 - Article
C2 - 29661060
AN - SCOPUS:85045686223
SN - 0898-2643
VL - 31
SP - 883
EP - 898
JO - Journal of Aging and Health
JF - Journal of Aging and Health
IS - 5
ER -