@inproceedings{ae30ae5e5bb94d5b9d2b969736b436d4,
title = "Mesoscope: AWeb-based Tool for Mesoscale Data Integration and Curation",
abstract = "Interest is growing for 3D models of the biological mesoscale, the intermediate scale between the nanometer scale of molecular structure and micrometer scale of cellular biology. However, it is currently difficult to gather, curate and integrate all the data required to define such models. To address this challenge we developed Mesoscope (mesoscope.scripps.edu/beta), a web-based data integration and curation tool. Mesoscope allows users to begin with a listing of molecules (such as data from proteomics), and to use resources at UniProt and the PDB to identify, prepare and validate appropriate structures and representations for each molecule, ultimately producing a portable output file used by CellPACK and other modeling tools for generation of 3D models of the biological mesoscale. The availability of this tool has proven essential in several exploratory applications, given the high complexity of mesoscale models and the heterogeneity of the available data sources.",
author = "L. Autin and M. Maritan and Barbaro, {B. A.} and A. Gardner and Olson, {A. J.} and M. Sanner and Goodsell, {D. S.}",
note = "Funding Information: This work was supported by grant GM120604 from the US National Institutes of Health. This is manuscript 29944 from the Scripps Research Institute. Publisher Copyright: {\textcopyright} 2020 The Author(s).; 2020 Workshop on Molecular Graphics and Visual Analysis of Molecular Data, MolVA 2020 ; Conference date: 25-05-2020",
year = "2020",
doi = "10.2312/molva.20201098",
language = "English (US)",
series = "MolVA 2020 - Workshop on Molecular Graphics and Visual Analysis of Molecular Data",
publisher = "The Eurographics Association",
pages = "23--31",
editor = "Jan Byska and Jan Byska and Michael Krone and Bjorn Sommer",
booktitle = "MolVA 2020 - Workshop on Molecular Graphics and Visual Analysis of Molecular Data",
}