Metabolism of nitrosamines by cytochrome P-450 isozymes.

C. S. Yang, Y. Y. Tu, J. Hong, C. Patten

Research output: Contribution to journalArticlepeer-review

6 Scopus citations


Results are presented to show that N-nitrosodimethylamine demethylase is P-450 mediated and N-nitrosodimethylamine is efficiently metabolized by specific P-450 isozymes inducible by a group of new inducers. The P-450-mediated N-nitrosodimethylamine demethylase also responds differently to inhibitors when activities are compared with those of classical monooxygenase systems.

Original languageEnglish (US)
Pages (from-to)423-428
Number of pages6
JournalIARC scientific publications
Issue number57
StatePublished - 1984
Externally publishedYes

All Science Journal Classification (ASJC) codes

  • Medicine(all)


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