Metal versus plastic for pancreatic pseudocyst drainage: Clinical outcomes and success

Reem Z. Sharaiha, Ersilia M. DeFilippis, Prashant Kedia, Monica Gaidhane, Christine Boumitri, Huei Wen Lim, Eugene Han, Harkarit Singh, Saad S. Ghumman, Thomas Kowalski, David Loren, Michel Kahaleh, Ali Siddiqui

Research output: Contribution to journalArticlepeer-review

86 Scopus citations


Background Endoscopic transmural drainage of pancreatic pseudocysts (PPs) by using double-pigtail (DP) plastic stents requires placement of multiple stents and can be restricted by inadequate drainage and leakage risk. Recently, the use of fully covered self-expanding metal stents (FCSEMSs) has been reported as an alternative to DP plastic stents. Objective To evaluate the clinical outcomes, success rate, and adverse events of EUS-guided drainage of PPs with DP plastic stents and FCSEMSs. Design Retrospective cohort study. Setting Two tertiary-care academic medical centers. Patients This study involved 230 patients (mean age, 52.6 years) with PPs who underwent EUS-guided transmural drainage including 118 that were drained by using DP plastic stents and 112 by using FCSEMSs. A transgastric approach was used in 210 patients (91%), and transduodenal drainage was performed in 20 patients (9%). Interventions Stent deployment under EUS guidance. Main Outcome Measurements Technical success, early adverse events, stent occlusion requiring reintervention, and long-term success. Results At 12-month follow-up after the initial procedure, complete resolution of PPs by using DP plastic stents was lower compared with those that underwent drainage with FCSEMSs (89% vs 98%; P =.01). Procedural adverse events were noted in 31% in the DP plastic stent group and 16% in the FCSEMS group (P =.006). On multivariable analysis, patients with plastic stents were 2.9 times more likely to experience adverse events (odds ratio 2.9; 95% confidence interval, 1.4-6.3). Limitations Retrospective study. Conclusion In patients with PPs, EUS-guided drainage by using FCSEMSs improves clinical outcomes and lowers adverse event rates compared with those drained with DP plastic stents.

Original languageEnglish (US)
Pages (from-to)822-827
Number of pages6
JournalGastrointestinal Endoscopy
Issue number5
StatePublished - Nov 2015
Externally publishedYes

All Science Journal Classification (ASJC) codes

  • Radiology Nuclear Medicine and imaging
  • Gastroenterology


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