Metastatic breast cancer: Preliminary results with oral hormonal therapy

Joseph C. Allegra, J. Bertino, P. Bonomi, P. Byrne, John Carpenter, R. Catalano, R. Creech, B. Dana, H. Durivage, L. Einhorn, D. Ettinger, F. A. Greco, E. Greenwald, I. Henderson, F. Holmes, Barry Kinzbrunner, S. Luedke, H. Muss, N. Nimeh, R. TalleyG. Wampler, Neal Weinreb, J. Weisberg, R. Wheeler, P. Wiernik

Research output: Contribution to journalArticle

16 Scopus citations


Hormonal therapy is very effective in the treatment of patients with metastatic breast cancer. Response to various therapies leads to improved quality of life and prolonged survival. This clinical trial compared two commonly utilized additive hormonal agents, tamoxifen citrate and megestrol acetate (Megace®). Preliminary data indicate equal efficacy and equal toxicity of these two hormones and suggests that both are suitable for first-line hormonal treatment of stage IV breast cancer.

Original languageEnglish (US)
Pages (from-to)61-64
Number of pages4
JournalSeminars in oncology
Issue number4 SUPPL. 6
StatePublished - Dec 1985


All Science Journal Classification (ASJC) codes

  • Hematology
  • Oncology

Cite this

Allegra, J. C., Bertino, J., Bonomi, P., Byrne, P., Carpenter, J., Catalano, R., Creech, R., Dana, B., Durivage, H., Einhorn, L., Ettinger, D., Greco, F. A., Greenwald, E., Henderson, I., Holmes, F., Kinzbrunner, B., Luedke, S., Muss, H., Nimeh, N., ... Wiernik, P. (1985). Metastatic breast cancer: Preliminary results with oral hormonal therapy. Seminars in oncology, 12(4 SUPPL. 6), 61-64.