MicroRNA function in NK-cell biology

Aimee M. Beaulieu, Natalie A. Bezman, Jang Eun Lee, Mehrdad Matloubian, Joseph C. Sun, Lewis L. Lanier

Research output: Contribution to journalArticlepeer-review

55 Scopus citations


The important role of microRNAs in directing immune responses has become increasingly clear. Here, we highlight discoveries uncovering the role of specific microRNAs in regulating the development and function of natural killer (NK) cells. Furthermore, we discuss the impact of NK cells on the entire immune system during global and specific microRNA ablation in the settings of inflammation, infection, and immune dysregulation.

Original languageEnglish (US)
Pages (from-to)40-52
Number of pages13
JournalImmunological Reviews
Issue number1
StatePublished - May 2013

All Science Journal Classification (ASJC) codes

  • Immunology and Allergy
  • Immunology


  • Cytotoxicity
  • Development
  • MicroRNA
  • NK
  • Natural killer


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