Miles run per week and HDL-C levels in healthy, middle-aged men: A dose- response relationship

P. F. Kokkinos, J. C. Holland, P. Narayan, J. A. Colleran, C. O. Dotson, V. Papademetriou

Research output: Contribution to journalArticlepeer-review

1 Scopus citations

Abstract

Regular exercise increases high-density lipoprotein cholesterol (HDL-C) levels. However, the exercise requirements for such an increase are not well- defined. We examined the association between miles run per week and HDL-C levels in healthy, nonsmoking males (n = 2,906; age = 43 ± 4). They were stratified based on the miles run per week. Six groups (G1-G6) with the respective mileage of 0, 5, 9, 12, 17, and 31 per week were established. A gradual increase in HDL-C was observed with increased miles (.308 mg/dl increase in HDL-C/mile). Most changes were noted in those jogging 7 to 14 miles per week at mild to moderate intensities. These results indicate a dose-response relationship between miles run per week and HDL-C levels. A mileage threshold for changes in HDL-C was not observed. However, when compared to the nonexercising group, HDL-C levels attained statistical significance at 7 or more miles per week.

Original languageEnglish (US)
Pages (from-to)10-15
Number of pages6
JournalCardiovascular Reviews and Reports
Volume16
Issue number8
StatePublished - 1995
Externally publishedYes

All Science Journal Classification (ASJC) codes

  • Cardiology and Cardiovascular Medicine

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