Milk-borne relaxin and reproductive system development

Carol A. Bagnell, Frank F. Bartol

Research output: Contribution to journalArticlepeer-review

2 Scopus citations


A window of opportunity for maternal programming of neonatal development is open in the first few days of life as a consequence of nursing. Colostrum (first milk) supports neonatal development by providing a conduit for delivery of milk-borne bioactive factors, exemplified by relaxin, from mother to offspring as proposed in the lactocrine hypothesis. Relaxin, a prototypical milk-borne bioactive factor, is detectable in colostrum from multiple species, including the pig. Thus, relaxin serves as a model for understanding lactocrine signals that support development of neonatal tissues.

Original languageEnglish (US)
Pages (from-to)15-16
Number of pages2
JournalItalian Journal of Anatomy and Embryology
Issue number1 SUPPL.
StatePublished - 2013

All Science Journal Classification (ASJC) codes

  • Anatomy
  • Embryology


  • Lactocrine
  • Milk
  • Relaxin
  • Uterus


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