Miller fisher variant of Guillain-Barré syndrome masquerading as acute sphenoid sinusitis with orbital apex syndrome

Amit Chaudhary, Tekchand Ramchand, Larry P. Frohman, James K. Liu, Jean Anderson Eloy

Research output: Contribution to journalArticlepeer-review

1 Scopus citations

Abstract

Miller Fisher syndrome (MFS), a variant of Guillain-Barré syndrome, is a rare disorder typically characterized by a triad of ataxia, areflexia, and ophthalmoplegia, which may have a highly variable clinical presentation. We report a case of MFS in a 45-year-old female presenting with sphenoid sinusitis and sixth nerve palsy. She underwent endoscopic sphenoid sinusotomy without improvement, had postoperative deterioration, was diagnosed with MFS, and was treated with intravenous immunoglobulin with complete response. Because of the potential severity of Guillain-Barré syndrome, great vigilance should be taken when examining sixth nerve palsies to prevent misdiagnosis and delay in treatment of the MFS variant of this disease.

Original languageEnglish (US)
Pages (from-to)970-972
Number of pages3
JournalLaryngoscope
Volume122
Issue number5
DOIs
StatePublished - May 2012

All Science Journal Classification (ASJC) codes

  • Otorhinolaryngology

Keywords

  • Guillain-Barré syndrome
  • Miller Fisher
  • Miller Fisher syndrome
  • Miller Fisher variant of Guillain-Barré syndrome
  • acute sphenoid sinusitis
  • acute viral sinusitis
  • cavernous sinus thrombosis
  • intracranial complication of sinusitis
  • ophthalmoplegia
  • orbital apex syndrome

Fingerprint Dive into the research topics of 'Miller fisher variant of Guillain-Barré syndrome masquerading as acute sphenoid sinusitis with orbital apex syndrome'. Together they form a unique fingerprint.

Cite this