1. The metabolism of parathion to para-nitrophenol (PNP) in redfish (Sciaenops ocellata) liver microsomes has been both identified and characterized. 2. This mixed-function oxidase (MFO) reaction in redfish requires NADPH and is inhibited by carbon monoxide. It exhibits a temperature optimum of 25°C but no clear pH optimum between 7.0-8.5. 3. Redfish hepatic microsomal MFOs were not induced by 2.5 days after a single i.p. injection of 88 mg Aroclor 1254/kg body wt, but under the same dosage and time conditions male albino Swiss mice were significantly induced (p < 0.05).
|Original language||English (US)|
|Number of pages||6|
|Journal||Comparative Biochemistry and Physiology. Part C, Comparative|
|Publication status||Published - 1984|
All Science Journal Classification (ASJC) codes