Abstract
1. The metabolism of parathion to para-nitrophenol (PNP) in redfish (Sciaenops ocellata) liver microsomes has been both identified and characterized. 2. This mixed-function oxidase (MFO) reaction in redfish requires NADPH and is inhibited by carbon monoxide. It exhibits a temperature optimum of 25°C but no clear pH optimum between 7.0-8.5. 3. Redfish hepatic microsomal MFOs were not induced by 2.5 days after a single i.p. injection of 88 mg Aroclor 1254/kg body wt, but under the same dosage and time conditions male albino Swiss mice were significantly induced (p < 0.05).
Original language | English (US) |
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Pages (from-to) | 177-182 |
Number of pages | 6 |
Journal | Comparative Biochemistry and Physiology. Part C, Comparative |
Volume | 79 |
Issue number | 1 |
DOIs | |
State | Published - 1984 |
Externally published | Yes |
All Science Journal Classification (ASJC) codes
- Immunology
- Pharmacology