Mixed-function oxidase studies in the redfish, sciaenops ocellata, from galveston bay, texas

Cynthia Hung Stahl, Lester G. Sultatos, Carl S. Hacker, Sheldon D. Murphy

Research output: Contribution to journalArticle

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Abstract

1. The metabolism of parathion to para-nitrophenol (PNP) in redfish (Sciaenops ocellata) liver microsomes has been both identified and characterized. 2. This mixed-function oxidase (MFO) reaction in redfish requires NADPH and is inhibited by carbon monoxide. It exhibits a temperature optimum of 25°C but no clear pH optimum between 7.0-8.5. 3. Redfish hepatic microsomal MFOs were not induced by 2.5 days after a single i.p. injection of 88 mg Aroclor 1254/kg body wt, but under the same dosage and time conditions male albino Swiss mice were significantly induced (p < 0.05).

Original languageEnglish (US)
Pages (from-to)177-182
Number of pages6
JournalComparative Biochemistry and Physiology. Part C, Comparative
Volume79
Issue number1
DOIs
Publication statusPublished - 1984

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All Science Journal Classification (ASJC) codes

  • Immunology
  • Pharmacology

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