Mixed-function oxidase studies in the redfish, sciaenops ocellata, from galveston bay, texas

Cynthia Hung Stahl, Lester Sultatos, Carl S. Hacker, Sheldon D. Murphy

Research output: Contribution to journalArticle

3 Citations (Scopus)

Abstract

1. The metabolism of parathion to para-nitrophenol (PNP) in redfish (Sciaenops ocellata) liver microsomes has been both identified and characterized. 2. This mixed-function oxidase (MFO) reaction in redfish requires NADPH and is inhibited by carbon monoxide. It exhibits a temperature optimum of 25°C but no clear pH optimum between 7.0-8.5. 3. Redfish hepatic microsomal MFOs were not induced by 2.5 days after a single i.p. injection of 88 mg Aroclor 1254/kg body wt, but under the same dosage and time conditions male albino Swiss mice were significantly induced (p < 0.05).

Original languageEnglish (US)
Pages (from-to)177-182
Number of pages6
JournalComparative Biochemistry and Physiology. Part C, Comparative
Volume79
Issue number1
DOIs
StatePublished - Jan 1 1984
Externally publishedYes

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Chlorodiphenyl (54% Chlorine)
Parathion
Nitrophenols
Liver Microsomes
Carbon Monoxide
Mixed Function Oxygenases
NADP
Injections
Temperature
Liver

All Science Journal Classification (ASJC) codes

  • Immunology
  • Pharmacology

Cite this

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abstract = "1. The metabolism of parathion to para-nitrophenol (PNP) in redfish (Sciaenops ocellata) liver microsomes has been both identified and characterized. 2. This mixed-function oxidase (MFO) reaction in redfish requires NADPH and is inhibited by carbon monoxide. It exhibits a temperature optimum of 25°C but no clear pH optimum between 7.0-8.5. 3. Redfish hepatic microsomal MFOs were not induced by 2.5 days after a single i.p. injection of 88 mg Aroclor 1254/kg body wt, but under the same dosage and time conditions male albino Swiss mice were significantly induced (p < 0.05).",
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Mixed-function oxidase studies in the redfish, sciaenops ocellata, from galveston bay, texas. / Stahl, Cynthia Hung; Sultatos, Lester; Hacker, Carl S.; Murphy, Sheldon D.

In: Comparative Biochemistry and Physiology. Part C, Comparative, Vol. 79, No. 1, 01.01.1984, p. 177-182.

Research output: Contribution to journalArticle

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T1 - Mixed-function oxidase studies in the redfish, sciaenops ocellata, from galveston bay, texas

AU - Stahl, Cynthia Hung

AU - Sultatos, Lester

AU - Hacker, Carl S.

AU - Murphy, Sheldon D.

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