@article{ed84efd16c534184a34f53b9a8e286e5,
title = "Modelling the impact of an HIV testing intervention on HIV transmission among men who have sex with men in China",
abstract = "Objectives: An intervention developed through participatory crowdsourcing methods increased HIV self-testing among men who have sex with men [MSM; relative risk (RR) = 1.89]. We estimated the long-term impact of this intervention on HIV transmission among MSM in four cities (Guangzhou, Shenzhen, Jinan and Qingdao). Methods: A mathematical model of HIV transmission, testing and treatment among MSM in China was parameterized using city-level demographic and sexual behaviour data and calibrated to HIV prevalence, diagnosis and antiretroviral therapy (ART) coverage data. The model was used to project the HIV infections averted over 20 years (2016–2036) from the intervention to increase self-testing, compared with current testing rates. Results: Running the intervention once would avert < 2.2% infections over 20 years. Repeating the intervention (RR = 1.89) annually would avert 6.4–10.7% of new infections, while further increases in the self-testing rate (hypothetical RR = 3) would avert 11.7–20.7% of new infections. Conclusions: Repeated annual interventions would give a three- to seven-fold increase in long-term impact compared with a one-off intervention. Other interventions will be needed to more effectively reduce the HIV burden in this population.",
keywords = "HIV, MSM, crowdsourcing, self-testing intervention",
author = "Booton, {Ross D.} and Ong, {Jason J.} and Amy Lee and Aifeng Liu and Wenting Huang and Chongyi Wei and Weiming Tang and Wei Ma and Peter Vickerman and Tucker, {Joseph D.} and Mitchell, {Kate M.}",
note = "Funding Information: We thank Fan Yang and Haochu Li for providing helpful feedback on the manuscript. We also thank Haochu Li for their help in the early phases of this project. Conflict of interest: KMM has received an honorarium from Gilead for speaking outside of the submitted work. All other authors have no competing interests. Financial disclosure: This work was funded by the National Key Research and Development Program of China (2017YFE0103800) and the NIH (NIAID 1R01AI114310). RDB and KMM also acknowledge the MRC Centre for Global Infectious Disease Analysis, which is jointly funded by the UK Medical Research Council (MRC) and the UK Department for International Development (DFID) under the MRC/DFID Concordat agreement and is also part of the EDCTP2 programme supported by the European Union (MR/R015600/1). JJO was funded by the Australian National Health and Medical Research Council (APP1104781). PV also acknowledges the UK National Institute of Health Research-funded Health Protection Research Unit in Evaluation of Interventions at the University of Bristol. Funding Information: This work was funded by the National Key Research and Development Program of China (2017YFE0103800) and the NIH (NIAID 1R01AI114310). RDB and KMM also acknowledge the MRC Centre for Global Infectious Disease Analysis, which is jointly funded by the UK Medical Research Council (MRC) and the UK Department for International Development (DFID) under the MRC/DFID Concordat agreement and is also part of the EDCTP2 programme supported by the European Union (MR/R015600/1). JJO was funded by the Australian National Health and Medical Research Council (APP1104781). PV also acknowledges the UK National Institute of Health Research‐funded Health Protection Research Unit in Evaluation of Interventions at the University of Bristol. Financial disclosure: Publisher Copyright: {\textcopyright} 2021 The Authors. HIV Medicine published by John Wiley & Sons Ltd on behalf of British HIV Association",
year = "2021",
month = jul,
doi = "10.1111/hiv.13063",
language = "English (US)",
volume = "22",
pages = "467--477",
journal = "HIV Medicine",
issn = "1464-2662",
publisher = "Wiley-Blackwell",
number = "6",
}