Molecular cloning and characterization of the pgm gene encoding phosphoglucomutase of Escherichia coli

M. Lu, N. Kleckner

Research output: Contribution to journalComment/debatepeer-review

83 Scopus citations

Abstract

We report here the identification and characterization of pgm, a gene in Escherichia coli that encodes the enzyme phosphoglucomutase, specifically required for the catalysis of the interconversion of glucose 1-phosphate and glucose 6-phosphate. The predicted amino acid sequence of the pgm gene is highly conserved in E. coli, Acetobacter xylinum, Saccharomyces cerevisiae, rabbits, and humans. pgm deletion mutant strains are deficient in phosphoglucomutase activity.

Original languageEnglish (US)
Pages (from-to)5847-5851
Number of pages5
JournalJournal of bacteriology
Volume176
Issue number18
DOIs
StatePublished - 1994
Externally publishedYes

All Science Journal Classification (ASJC) codes

  • Microbiology
  • Molecular Biology

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