Abstract
An account is given on work towards overcoming two of the barriers to antisense effectiveness. The first work concerns the development of molecular targeting strategies for the delivery of high concentrations of active oligonucleotide to a specific cell type. Second, given the variable and often poor affinity of antisense sequences, strategies for the rational design of high affinity antisense sequences are detailed.
| Original language | English (US) |
|---|---|
| Title of host publication | American Society of Mechanical Engineers, Bioengineering Division (Publication) BED |
| Publisher | ASME |
| Pages | 677-678 |
| Number of pages | 2 |
| Volume | 42 |
| ISBN (Print) | 0791816117 |
| State | Published - 1999 |
| Externally published | Yes |
| Event | 1999 Bioengineering Conference - Big Sky, MT, USA Duration: Jun 16 1999 → Jun 20 1999 |
Other
| Other | 1999 Bioengineering Conference |
|---|---|
| City | Big Sky, MT, USA |
| Period | 6/16/99 → 6/20/99 |
All Science Journal Classification (ASJC) codes
- Engineering(all)