Antihypertensive treatments were given to young and adult SHRs, to prevent and reverse hypertension, respectively. Cardiac hypertrophy and the steady state level of the 'fetal' genes, ANP, α-skeletal actin (α-skA), and β myosin heavy chain (β-MHC) mRNAs were assessed. Our findings show that the reduction of blood pressure does not consistently result in a similar regression of the 'fetal gene program'.
|Original language||English (US)|
|Number of pages||9|
|Journal||Advances in experimental medicine and biology|
|State||Published - Jan 1 1995|
All Science Journal Classification (ASJC) codes
- Biochemistry, Genetics and Molecular Biology(all)