Monoclonal antibodies used as probes for the structural organization of the central region of fibronectin

M. Dziadek, H. Richter, M. Schachner, R. Timpl

Research output: Contribution to journalArticlepeer-review

33 Scopus citations

Abstract

Two monoclonal mouse antibodies against human plasma fibronectin were compared in their reactivity for proteolytic fragments of the antigen by enzyme immunoassay and immunoblotting. These antibodies were shown to react with two different structures within a short segment (about 30 kDa) located about one-third away from the C-terminus of the fibronectin chains.

Original languageEnglish (US)
Pages (from-to)321-325
Number of pages5
JournalFEBS Letters
Volume155
Issue number2
DOIs
StatePublished - May 8 1983

All Science Journal Classification (ASJC) codes

  • Biophysics
  • Structural Biology
  • Biochemistry
  • Molecular Biology
  • Genetics
  • Cell Biology

Keywords

  • Central region structure
  • Fibronectin
  • Immunoblotting
  • Monoclonal antibody

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