Multi-ligand interactions with receptor-like protein tyrosine phosphatase β: Implications for intercellular signaling

Elior Peles, Joseph Schlessinger, Martin Grumet

Research output: Contribution to journalArticlepeer-review

93 Scopus citations

Abstract

Receptor-like protein tyrosine phosphatase β (RPTPβ) shows structural and functional similarity to cell adhesion molecules (CAMs). It binds to several neuronal CAMs and extracellular matrix (ECM) proteins that combine to form cell-recognition complexes. Here, the authors discuss the implications of such complexes for intercellular signaling, and the regulation of RPTP activity by cell-cell and cell-ECM contact.

Original languageEnglish (US)
Pages (from-to)121-124
Number of pages4
JournalTrends in Biochemical Sciences
Volume23
Issue number4
DOIs
StatePublished - Dec 1 1998
Externally publishedYes

All Science Journal Classification (ASJC) codes

  • Biochemistry
  • Molecular Biology

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