Multipoint optogenetic control of neural activity with tapered and nanostructured optical fibers

Ferruccio Pisanello; Leonardo Sileo; Andrea Della Patria; Marco Pisanello; Massimo De Vittorio; Ian A. Oldenburg; Bernardo L. Sabatini; John A. Assad

doi:10.1109/MMS.2015.7375492

Multipoint optogenetic control of neural activity with tapered and nanostructured optical fibers

Ferruccio Pisanello, Leonardo Sileo, Andrea Della Patria, Marco Pisanello, Massimo De Vittorio, Ian A. Oldenburg, Bernardo L. Sabatini, John A. Assad

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

1 Scopus citations

Abstract

The combination of genetics and optics for simultaneous control and monitor of neural activity has recently represented a revolution for the investigation of functional connectivity in the living mammalian brain, since it allows to identify the role of specific classes of neurons within specific neural circuits. At the same time, there is the widespread agreement that, for this technique to be successful, new methods and technologies for better matching with the incredibly complex topology of brain networks are needed. In this work we review our recent approach for multisite light delivery in the mouse brain [1], allowing the stimulation of selected portions of neural tissue along the edge of a minimally invasive, nanostructured and gold coated tapered optical fiber.

Original language	English (US)
Title of host publication	2015 IEEE 15th Mediterranean Microwave Symposium, MMS 2015
Publisher	IEEE Computer Society
ISBN (Electronic)	9781467376020
DOIs	https://doi.org/10.1109/MMS.2015.7375492
State	Published - Jan 7 2015
Externally published	Yes
Event	15th IEEE Mediterranean Microwave Symposium, MMS 2015 - Lecce, Italy Duration: Nov 30 2015 → Dec 2 2015

Publication series

Name	Mediterranean Microwave Symposium
Volume	2015-January
ISSN (Print)	2157-9822
ISSN (Electronic)	2157-9830

Conference

Conference	15th IEEE Mediterranean Microwave Symposium, MMS 2015
Country/Territory	Italy
City	Lecce
Period	11/30/15 → 12/2/15

All Science Journal Classification (ASJC) codes

Electrical and Electronic Engineering

Keywords

biophotonics
brain
neural activity
neurophotonics
optical fibers
optogenetics

Access to Document

10.1109/MMS.2015.7375492

Cite this

Pisanello, F., Sileo, L., Patria, A. D., Pisanello, M., De Vittorio, M., Oldenburg, I. A., Sabatini, B. L., & Assad, J. A. (2015). Multipoint optogenetic control of neural activity with tapered and nanostructured optical fibers. In 2015 IEEE 15th Mediterranean Microwave Symposium, MMS 2015 Article 7375492 (Mediterranean Microwave Symposium; Vol. 2015-January). IEEE Computer Society. https://doi.org/10.1109/MMS.2015.7375492

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title = "Multipoint optogenetic control of neural activity with tapered and nanostructured optical fibers",

abstract = "The combination of genetics and optics for simultaneous control and monitor of neural activity has recently represented a revolution for the investigation of functional connectivity in the living mammalian brain, since it allows to identify the role of specific classes of neurons within specific neural circuits. At the same time, there is the widespread agreement that, for this technique to be successful, new methods and technologies for better matching with the incredibly complex topology of brain networks are needed. In this work we review our recent approach for multisite light delivery in the mouse brain [1], allowing the stimulation of selected portions of neural tissue along the edge of a minimally invasive, nanostructured and gold coated tapered optical fiber.",

keywords = "biophotonics, brain, neural activity, neurophotonics, optical fibers, optogenetics",

author = "Ferruccio Pisanello and Leonardo Sileo and Patria, {Andrea Della} and Marco Pisanello and {De Vittorio}, Massimo and Oldenburg, {Ian A.} and Sabatini, {Bernardo L.} and Assad, {John A.}",

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year = "2015",

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day = "7",

doi = "10.1109/MMS.2015.7375492",

language = "English (US)",

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Pisanello, F, Sileo, L, Patria, AD, Pisanello, M, De Vittorio, M, Oldenburg, IA, Sabatini, BL & Assad, JA 2015, Multipoint optogenetic control of neural activity with tapered and nanostructured optical fibers. in 2015 IEEE 15th Mediterranean Microwave Symposium, MMS 2015., 7375492, Mediterranean Microwave Symposium, vol. 2015-January, IEEE Computer Society, 15th IEEE Mediterranean Microwave Symposium, MMS 2015, Lecce, Italy, 11/30/15. https://doi.org/10.1109/MMS.2015.7375492

Multipoint optogenetic control of neural activity with tapered and nanostructured optical fibers. / Pisanello, Ferruccio; Sileo, Leonardo; Patria, Andrea Della et al.
2015 IEEE 15th Mediterranean Microwave Symposium, MMS 2015. IEEE Computer Society, 2015. 7375492 (Mediterranean Microwave Symposium; Vol. 2015-January).

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

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Multipoint optogenetic control of neural activity with tapered and nanostructured optical fibers

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Keywords

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