TY - JOUR
T1 - Mutations that alter the helix‐turn‐helix region of the spollAC protein
T2 - a Bacillus subtilis sporulation‐specific sigma factor
AU - Yudkin, M. D.
AU - Millonig, J. H.
AU - Appleby, L.
PY - 1989/2
Y1 - 1989/2
N2 - It has previously been shown that spollAC561, a mutation that diminishes the incidence of sporulation by more than six orders of magnitude, alters the residue at position 13 of the helix‐turn‐helix region of the sporulation‐specific sigma factor encoded by spoll AC from valine to methionine (Yudkin, 1987b). We have now found that four spontaneous revertants, which sporulate at an incidence of 30‐60%, all contain transitions within the codon that was altered by spo‐561. The mutant methionine is replaced by isoleucine in two revertants, and by threonine in the other two.
AB - It has previously been shown that spollAC561, a mutation that diminishes the incidence of sporulation by more than six orders of magnitude, alters the residue at position 13 of the helix‐turn‐helix region of the sporulation‐specific sigma factor encoded by spoll AC from valine to methionine (Yudkin, 1987b). We have now found that four spontaneous revertants, which sporulate at an incidence of 30‐60%, all contain transitions within the codon that was altered by spo‐561. The mutant methionine is replaced by isoleucine in two revertants, and by threonine in the other two.
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U2 - 10.1111/j.1365-2958.1989.tb01815.x
DO - 10.1111/j.1365-2958.1989.tb01815.x
M3 - Article
C2 - 2503677
AN - SCOPUS:0024454185
SN - 0950-382X
VL - 3
SP - 257
EP - 259
JO - Molecular microbiology
JF - Molecular microbiology
IS - 2
ER -