Nanoporous gold: A biomaterial for microfabricated drug-delivery platforms

Erkin Seker, Yevgeny Berdichevsky, Kevin J. Staley, Martin L. Yarmush

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

Nanoporous gold (np-Au) is a promising nanostructured material with many desirable properties, including large surface area-to-volume ratio, corrosion resistance, high conductivity, and well-studied thiol-based surface chemistry. While np-Au has been used in a variety of applications, from fuel cells to electrochemical sensors, its interface with biology, where many of its exciting applications lie, is surprisingly non-existent. This paper reports on drug delivery from np-Au thin films for modifying cell proliferation in situ. We expect that establishing np-Au as a biomaterial with drug delivery capabilities will create new opportunities for engineering advanced BioMEMS devices that can monitor and modulate biological processes in both in vitro and in vivo settings.

Original languageEnglish (US)
Title of host publicationMEMS, BioMEMS and Bioelectronics - Materials and Devices
Pages147-152
Number of pages6
DOIs
StatePublished - Aug 20 2012
Event2011 MRS Fall Meeting - Boston, MA, United States
Duration: Nov 28 2011Dec 2 2011

Publication series

NameMaterials Research Society Symposium Proceedings
Volume1415
ISSN (Print)0272-9172

Other

Other2011 MRS Fall Meeting
CountryUnited States
CityBoston, MA
Period11/28/1112/2/11

All Science Journal Classification (ASJC) codes

  • Materials Science(all)
  • Condensed Matter Physics
  • Mechanics of Materials
  • Mechanical Engineering

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