Neurite Extension by Mouse Neuroblastoma: Evidence for Two Modes of Induction

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The induction of neurite extension by mouse neuroblastoma cells in vitro can be reversed by adding colchicine or cytochalasin B (CB) to the culture medium. The relative sensitivity of the neurites to retraction is a function of the method used to induce extension. Cells incubated in the absence of serum or in the presence of serum and dibutyryl cyclic-AMP are sensitive to both colchicine and CB; cells incubated in serum-free medium containing either cycloheximide or dimethylsulphoxide are sensitive only to colchicine.

Original languageEnglish (US)
Pages (from-to)319-322
Number of pages4
Issue number5
StatePublished - 1973
Externally publishedYes

All Science Journal Classification (ASJC) codes

  • Molecular Biology
  • Developmental Biology
  • Cell Biology
  • Cancer Research


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