Neurologic consequences of HTLV-II infection in injection-drug users

G. Dooneief, R. Marlink, K. Bell, K. Marder, B. Renjifo, Y. Stern, R. Mayeux

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Abstract

Several case reports have suggested an association between human T-cell lymphotropic virus type II (HTLV-II) infection and chronic neurologic disease. We performed serial neurologic examinations in injection-drug users (IDU), a group known to be at increased risk for HTLV-II infection. At baseline, those infected with HTLV-II alone, human immunodeficiency virus (HIV) alone, or both were significantly more likely to have neurologic disability than uninfected subjects. Longitudinally, HTLV-II infection was independently associated with the development of global neurologic disability and neuropathy, suggesting that HTLV-II causes neurologic disease.

Original languageEnglish (US)
Pages (from-to)1556-1560
Number of pages5
JournalNeurology
Volume46
Issue number6
DOIs
StatePublished - Jun 1996
Externally publishedYes

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All Science Journal Classification (ASJC) codes

  • Clinical Neurology

Cite this

Dooneief, G., Marlink, R., Bell, K., Marder, K., Renjifo, B., Stern, Y., & Mayeux, R. (1996). Neurologic consequences of HTLV-II infection in injection-drug users. Neurology, 46(6), 1556-1560. https://doi.org/10.1212/WNL.46.6.1556