Neuronal and glial 3D chromatin architecture informs the cellular etiology of brain disorders

Keyphrases

• Etiology 100%
• Brain Disorders 100%
• 3D Chromatin Structure 100%
• Genetic Risk 66%
• Human Brain 66%
• Bipolar Disorder 66%
• Alzheimer's Disease 66%
• Gene Regulatory Network 66%
• Microglia 33%
• Projection Neurons 33%
• Oligodendrocyte 33%
• Genetic Variation 33%
• Schizophrenia 33%
• Transcriptomics 33%
• Glia 33%
• Schizophrenia Symptoms 33%
• Type-specific 33%
• Parvalbumin Interneurons 33%
• Non-coding 33%
• Regulatory Landscape 33%
• Disease-associated 33%
• GABAergic 33%
• Cell-type-specific Gene Expression 33%
• Glutamatergic 33%
• Epigenetic Dysregulation 33%
• Disease Risk 33%
• Cellular Heterogeneity 33%
• Cell Class 33%
• Upper Layer Neurons 33%
• Non-coding Elements 33%
• Chromosome Conformation 33%
• Gene Regulatory Landscape 33%

Biochemistry, Genetics and Molecular Biology

• Genetic Risk 100%
• Genetic Divergence 50%
• Epigenetics 50%
• Enhancer Region 50%
• Genetic Variation 50%
• Transcriptomics 50%
• Regulatory Network 50%
• Oligodendrocyte 50%
• Interneuron 50%
• Glutamatergic 50%
• Conformation 50%
• Locus Control Region 50%
• Microglia 50%
• Parvalbumin 50%
• Gene Regulatory Network 50%

Neuroscience

• Brain Disease 100%
• Bipolar Disorder 66%
• Alzheimer's Disease 66%
• Microglia 33%
• Oligodendrocyte 33%
• Genetic Variation 33%
• Glia 33%
• Parvalbumin 33%
• Regulator Gene 33%
• Enhancer Region 33%
• Gene Regulatory Network 33%
• Transcriptomics 33%
• Interneuron 33%