New biomaterials derived from backbone modified poly(amino acids)

Research output: Contribution to journalConference articlepeer-review

Abstract

The central theme of our synthetic work is to explore reaction schemes in which the amino acids are linked together via their side chains by non-amide bonds. This synthetic approach can give rise to poly(amino acids) with modified backbone structures. In analogy to widely used terminology in peptide chemistry, the name 'pseudopoly(amino acids)' has been suggested for this new class of polymers. Since in pseudopoly(amino acids) the conventional peptide bonds have been replaced by a variety of 'non-amide' linkages, it is conceivable that pseudopoly(amino acids) may not suffer from the disadvantages that have limited the applicability of conventional poly(amino acids). We are therefore currently investigating to which extent pseudopoly(amino acids) can be employed as degradable biomaterials.

Original languageEnglish (US)
Pages (from-to)153-157
Number of pages5
JournalPolymeric Materials Science and Engineering, Proceedings of the ACS Division of Polymeric Materials Science and Engineering
Volume63
StatePublished - 1990
EventProceedings of the ACS Division of Polymeric Materials: Science and Engineering - Washington, DC, USA
Duration: Aug 26 1990Aug 31 1990

All Science Journal Classification (ASJC) codes

  • Chemical Engineering (miscellaneous)
  • Polymers and Plastics

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