New type sesquiterpene lactone from almond hulls (Prunus amygdalus Batsch)

Shengmin Sang, Xiaofang Cheng, Hui Yin Fu, Den En Shieh, Naisheng Bai, Karen Lapsley, Ruth E. Stark, Robert T. Rosen, Chi Tang Ho

Research output: Contribution to journalArticlepeer-review

27 Scopus citations

Abstract

A new unusual sesquiterpene lactone, named amygdalactone, was isolated from the hulls of almond (Prunus amygdalus). Complete assignment of the proton and carbon chemical shifts for the new lactone was accomplished on the basis of high-resolution 1D and 2D NMR data. Amygdalactone represents a new class of sesquiterpene with cyclohexa[7,12-g]octalactone ring system. The cytotoxic activity of amygdalactone was determined.

Original languageEnglish (US)
Pages (from-to)2547-2549
Number of pages3
JournalTetrahedron Letters
Volume43
Issue number14
DOIs
StatePublished - Apr 1 2002

All Science Journal Classification (ASJC) codes

  • Biochemistry
  • Drug Discovery
  • Organic Chemistry

Keywords

  • Almond hulls
  • Amygdalactone
  • Prunus amygdalus
  • Rosaceae
  • Sesquiterpene lactone

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