Normal distribution of apolipoprotein E alleles in progressive supranuclear palsy

A. Anouti; K. Schmidt; K. E. Lyons; J. P. Hubble; G. Schellenberg; L. I. Golbe; A. E. Lang; N. Galvez-Jimenez; L. Hershey; W. C. Koller

doi:10.1212/WNL.46.4.1156

Normal distribution of apolipoprotein E alleles in progressive supranuclear palsy

A. Anouti, K. Schmidt, K. E. Lyons, J. P. Hubble, G. Schellenberg, L. I. Golbe, A. E. Lang, N. Galvez-Jimenez, L. Hershey, W. C. Koller

Robert Wood Johnson Medical School (RWJMS), Neurology

Research output: Contribution to journal › Article › peer-review

25 Scopus citations

Abstract

Apolipoprotein E (Apo E) genotype is a genetic risk factor influencing the development of Alzheimer's disease (AD). Progressive supranuclear palsy (PSP), like AD, is a dementing illness with neurofibrillary tangles. We determined the frequencies of Apo E alleles in 52 PSP patients and 52 age- and gender-matched controls. The distribution of Apo E allele frequencies and genotypes showed no difference between PSP and controls. Apo E allele status does not influence the development of PSP.

Original language	English (US)
Pages (from-to)	1156-1157
Number of pages	2
Journal	Neurology
Volume	46
Issue number	4
DOIs	https://doi.org/10.1212/WNL.46.4.1156
State	Published - Apr 1996

All Science Journal Classification (ASJC) codes

Clinical Neurology

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title = "Normal distribution of apolipoprotein E alleles in progressive supranuclear palsy",

abstract = "Apolipoprotein E (Apo E) genotype is a genetic risk factor influencing the development of Alzheimer's disease (AD). Progressive supranuclear palsy (PSP), like AD, is a dementing illness with neurofibrillary tangles. We determined the frequencies of Apo E alleles in 52 PSP patients and 52 age- and gender-matched controls. The distribution of Apo E allele frequencies and genotypes showed no difference between PSP and controls. Apo E allele status does not influence the development of PSP.",

author = "A. Anouti and K. Schmidt and Lyons, {K. E.} and Hubble, {J. P.} and G. Schellenberg and Golbe, {L. I.} and Lang, {A. E.} and N. Galvez-Jimenez and L. Hershey and Koller, {W. C.}",

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doi = "10.1212/WNL.46.4.1156",

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T1 - Normal distribution of apolipoprotein E alleles in progressive supranuclear palsy

AU - Anouti, A.

AU - Schmidt, K.

AU - Lyons, K. E.

AU - Hubble, J. P.

AU - Schellenberg, G.

AU - Golbe, L. I.

AU - Lang, A. E.

AU - Galvez-Jimenez, N.

AU - Hershey, L.

AU - Koller, W. C.

PY - 1996/4

Y1 - 1996/4

N2 - Apolipoprotein E (Apo E) genotype is a genetic risk factor influencing the development of Alzheimer's disease (AD). Progressive supranuclear palsy (PSP), like AD, is a dementing illness with neurofibrillary tangles. We determined the frequencies of Apo E alleles in 52 PSP patients and 52 age- and gender-matched controls. The distribution of Apo E allele frequencies and genotypes showed no difference between PSP and controls. Apo E allele status does not influence the development of PSP.

AB - Apolipoprotein E (Apo E) genotype is a genetic risk factor influencing the development of Alzheimer's disease (AD). Progressive supranuclear palsy (PSP), like AD, is a dementing illness with neurofibrillary tangles. We determined the frequencies of Apo E alleles in 52 PSP patients and 52 age- and gender-matched controls. The distribution of Apo E allele frequencies and genotypes showed no difference between PSP and controls. Apo E allele status does not influence the development of PSP.

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JO - Neurology

JF - Neurology

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ER -

Normal distribution of apolipoprotein E alleles in progressive supranuclear palsy

Abstract

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