Now, swing your partner! 3D-domain switching of WASP activates Arp2/3 complex

Research output: Contribution to journalShort surveypeer-review

3 Scopus citations

Abstract

Structural and functional analysis of WASP family cell signaling proteins shows that the same residues that are sequestered upon GTPase binding in the autoinhibited state are involved in binding to and activating Arp2/3 complex, WASP's downstream partner in the signaling cascade.

Original languageEnglish (US)
Pages (from-to)583-584
Number of pages2
JournalNature Structural Biology
Volume10
Issue number8
DOIs
StatePublished - Aug 1 2003

All Science Journal Classification (ASJC) codes

  • Structural Biology
  • Biochemistry
  • Genetics

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