Abstract
Structural and functional analysis of WASP family cell signaling proteins shows that the same residues that are sequestered upon GTPase binding in the autoinhibited state are involved in binding to and activating Arp2/3 complex, WASP's downstream partner in the signaling cascade.
Original language | English (US) |
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Pages (from-to) | 583-584 |
Number of pages | 2 |
Journal | Nature Structural Biology |
Volume | 10 |
Issue number | 8 |
DOIs | |
State | Published - Aug 1 2003 |
All Science Journal Classification (ASJC) codes
- Structural Biology
- Biochemistry
- Genetics