Magnesium Calcium (MgCa) alloys have become attractive orthopedic biomaterials due to their biodegradability, biocompatibility, and congruent mechanical properties with bone tissues. However, process mechanics of machining biomedical MgCa alloys is poorly understood. Mechanical properties of the biomedical MgCa alloy up to high strain rates and large strains are determined, for the first time, by using the combined quasi-static compression and split-Hopkinson pressure bar (SHPB) testing methods. A finite element simulation model of high speed cutting MgCa alloy has been developed using the obtained material properties at quasi-static and dynamic conditions. The characteristics of chip morphology, temperatures, and other process variables in the cutting process are investigated. The findings of this paper provide useful insights for understanding and improving high speed cutting of MgCa alloys.