One-pot, 18-component synthesis of an octahedral nanocontainer molecule

Xuejun Liu, Yong Liu, Gina Li, Ralf Warmuth

Research output: Contribution to journalArticlepeer-review

166 Scopus citations


A whole in one! The octahedral nanocontainer 3 composed of six cavitands 1 that are connected together by 12 diamino bridging units 2 through 24 imine bonds was synthesized in nearly quantitative yield in a one-pot reaction. Molecular mechanics calculations and NMR experiments suggest that this container has a diameter of 3.2 Å and an inner cavity volume of about 1700 Å3. (Figure Presented).

Original languageEnglish (US)
Pages (from-to)901-904
Number of pages4
JournalAngewandte Chemie - International Edition
Issue number6
StatePublished - Jan 30 2006

All Science Journal Classification (ASJC) codes

  • Catalysis
  • Chemistry(all)


  • Cavitands
  • Host-guest systems
  • Multicomponent reactions
  • Supramolecular chemistry

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