Open ring enhancement in atypical brain demyelination

Vijayakumar Javalkar, Marc Manix, Jon Wilson, Anil Nanda

Research output: Contribution to journalArticlepeer-review

9 Scopus citations


Open ring enhancement is considered highly specific for atypical demyelination. In this report we present a patient with a history of headache, ataxia and sensory disturbances in the lower extremities. A cranial MRI scan showed a large frontal lesion with mass effect, midline shift and with open ring enhancement. These findings are characteristics of tumefactive multiple sclerosis. Such lesions can be confused with neoplasms and abscesses. Open ring enhancement may help in differentiating atypical demyelination from a neoplasm or an abscess.

Original languageEnglish (US)
Pages (from-to)910-912
Number of pages3
JournalJournal of Clinical Neuroscience
Issue number6
StatePublished - Jun 1 2012
Externally publishedYes

All Science Journal Classification (ASJC) codes

  • Surgery
  • Neurology
  • Clinical Neurology
  • Physiology (medical)


  • Imaging features
  • Open ring enhancement
  • Tumefactive multiple sclerosis

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