Optimization of gray/white matter contrast with fast inversion recovery for myelin suppression: A comparison of fast spin-echo and echo-planar MR imaging sequences

Leo J. Wolansky, Steven G. Finden, Janet Chen, Rafik Hanna, Andrei I. Holodny, Imtiaz Ahmad, Wen Ching Liu, Sohail Contractor

Research output: Contribution to journalArticle

8 Scopus citations

Abstract

We compared two MR imaging sequences, fast inversion recovery for myelin suppression (FIRMS) and echo-planar FIRMS (EP-FIRMS), for depicting gray/white matter contrast. In 18 patients, the frequency bandwidth (BW) was optimized for each sequence; in nine patients, the BW was held constant. In the BW-optimized group, the mean contrast-to-noise ratio (C/N) was three times higher with the FIRMS sequence. In the BW-constant group, the mean C/N was 27% higher with the EP-FIRMS sequence; however, geometric distortion degraded the EP-FIRMS images excessively. For optimal gray/white contrast, FIRMS appears to be the superior pulse sequence.

Original languageEnglish (US)
Pages (from-to)1653-1657
Number of pages5
JournalAmerican Journal of Neuroradiology
Volume20
Issue number9
StatePublished - Nov 4 1999
Externally publishedYes

All Science Journal Classification (ASJC) codes

  • Radiology Nuclear Medicine and imaging
  • Clinical Neurology

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