Optimization of gray/white matter contrast with fast inversion recovery for myelin suppression: A comparison of fast spin-echo and echo-planar MR imaging sequences

Leo J. Wolansky, Steven G. Finden, Janet Chen, Rafik Hanna, Andrei I. Holodny, Imtiaz Ahmad, Wen Ching Liu, Sohail Contractor

Research output: Contribution to journalArticle

7 Citations (Scopus)

Abstract

We compared two MR imaging sequences, fast inversion recovery for myelin suppression (FIRMS) and echo-planar FIRMS (EP-FIRMS), for depicting gray/white matter contrast. In 18 patients, the frequency bandwidth (BW) was optimized for each sequence; in nine patients, the BW was held constant. In the BW-optimized group, the mean contrast-to-noise ratio (C/N) was three times higher with the FIRMS sequence. In the BW-constant group, the mean C/N was 27% higher with the EP-FIRMS sequence; however, geometric distortion degraded the EP-FIRMS images excessively. For optimal gray/white contrast, FIRMS appears to be the superior pulse sequence.

Original languageEnglish (US)
Pages (from-to)1653-1657
Number of pages5
JournalAmerican Journal of Neuroradiology
Volume20
Issue number9
StatePublished - Nov 4 1999
Externally publishedYes

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Echo-Planar Imaging
Myelin Sheath
Sequence Inversion
Noise
Gray Matter
White Matter

All Science Journal Classification (ASJC) codes

  • Radiology Nuclear Medicine and imaging
  • Clinical Neurology

Cite this

Wolansky, Leo J. ; Finden, Steven G. ; Chen, Janet ; Hanna, Rafik ; Holodny, Andrei I. ; Ahmad, Imtiaz ; Liu, Wen Ching ; Contractor, Sohail. / Optimization of gray/white matter contrast with fast inversion recovery for myelin suppression : A comparison of fast spin-echo and echo-planar MR imaging sequences. In: American Journal of Neuroradiology. 1999 ; Vol. 20, No. 9. pp. 1653-1657.
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abstract = "We compared two MR imaging sequences, fast inversion recovery for myelin suppression (FIRMS) and echo-planar FIRMS (EP-FIRMS), for depicting gray/white matter contrast. In 18 patients, the frequency bandwidth (BW) was optimized for each sequence; in nine patients, the BW was held constant. In the BW-optimized group, the mean contrast-to-noise ratio (C/N) was three times higher with the FIRMS sequence. In the BW-constant group, the mean C/N was 27{\%} higher with the EP-FIRMS sequence; however, geometric distortion degraded the EP-FIRMS images excessively. For optimal gray/white contrast, FIRMS appears to be the superior pulse sequence.",
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Optimization of gray/white matter contrast with fast inversion recovery for myelin suppression : A comparison of fast spin-echo and echo-planar MR imaging sequences. / Wolansky, Leo J.; Finden, Steven G.; Chen, Janet; Hanna, Rafik; Holodny, Andrei I.; Ahmad, Imtiaz; Liu, Wen Ching; Contractor, Sohail.

In: American Journal of Neuroradiology, Vol. 20, No. 9, 04.11.1999, p. 1653-1657.

Research output: Contribution to journalArticle

TY - JOUR

T1 - Optimization of gray/white matter contrast with fast inversion recovery for myelin suppression

T2 - A comparison of fast spin-echo and echo-planar MR imaging sequences

AU - Wolansky, Leo J.

AU - Finden, Steven G.

AU - Chen, Janet

AU - Hanna, Rafik

AU - Holodny, Andrei I.

AU - Ahmad, Imtiaz

AU - Liu, Wen Ching

AU - Contractor, Sohail

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AB - We compared two MR imaging sequences, fast inversion recovery for myelin suppression (FIRMS) and echo-planar FIRMS (EP-FIRMS), for depicting gray/white matter contrast. In 18 patients, the frequency bandwidth (BW) was optimized for each sequence; in nine patients, the BW was held constant. In the BW-optimized group, the mean contrast-to-noise ratio (C/N) was three times higher with the FIRMS sequence. In the BW-constant group, the mean C/N was 27% higher with the EP-FIRMS sequence; however, geometric distortion degraded the EP-FIRMS images excessively. For optimal gray/white contrast, FIRMS appears to be the superior pulse sequence.

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