Packaging of fat: An evolving model of lipid droplet assembly and expansion

Dawn L. Brasaemle, Nathan E. Wolins

Research output: Contribution to journalShort surveypeer-review

161 Scopus citations

Abstract

Lipid droplets (LDs) are organelles found in most types of cells in the tissues of vertebrates, invertebrates, and plants, as well as in bacteria and yeast. They differ from other organelles in binding a unique complement of proteins and lacking an aqueous core but share aspects of protein trafficking with secretory membrane compartments. In this minireview, we focus on recent evidence supporting an endoplasmic reticulum origin for LD formation and discuss recent findings regarding LD maturation and fusion.

Original languageEnglish (US)
Pages (from-to)2273-2279
Number of pages7
JournalJournal of Biological Chemistry
Volume287
Issue number4
DOIs
StatePublished - Jan 20 2012

All Science Journal Classification (ASJC) codes

  • Biochemistry
  • Molecular Biology
  • Cell Biology

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