Panophthalmitis due to clostridium septicum

Daniel C. Schickner, Alon Yarkoni, Paul Langer, Larry Frohman, Xue Chen, Robert Folberg, Lucian V. Del Priore

Research output: Contribution to journalArticlepeer-review

17 Scopus citations


Purpose To describe patient survival in a rare case of endogenous Clostridium septicum sepsis with panophthalmitis. Design Observational case report. Methods Both eyes of a female patient were examined in a hospital setting. Results A 68-year-old woman had right orbital pain, proptosis, panophthalmitis, mental confusion and fever for 2 days. Blood cultures were significant for Clostridium septicum. The patient did not improve after treatment with intravenous broad-spectrum antibiotics and the right eye was enucleated. The patient survived the acute infection and extensive systemic evaluation revealed an undiagnosed colon carcinoma that may have been responsible for colonization and vascular dissemination of Clostridium septicum. Conclusions Clostridium septicum panophthalmitis and sepsis can be the presenting sign in patients with unsuspected malignancies, particularly colon cancer. Patients can survive the infection with aggressive therapy with systemic antibiotics combined with removal of the infected tissue.

Original languageEnglish (US)
Pages (from-to)942-944
Number of pages3
JournalAmerican journal of ophthalmology
Issue number5
StatePublished - May 2004

All Science Journal Classification (ASJC) codes

  • Ophthalmology


Dive into the research topics of 'Panophthalmitis due to clostridium septicum'. Together they form a unique fingerprint.

Cite this