Pathophysiology of Campylobacter jejuni infections of humans

Trudy M. Wassenaar; Martin J. Blaser

doi:10.1016/S1286-4579(99)80520-6

Pathophysiology of Campylobacter jejuni infections of humans

Trudy M. Wassenaar, Martin J. Blaser

Research output: Contribution to journal › Review article › peer-review

158 Scopus citations

Abstract

Campylobacter jejuni and closely related organisms are major cause of human bacterial enteritis. These infections can lead to extraintestinal disease and severe long-term complications. Of these, neurological damage, apparently due to the immune response of the host, is the most striking. This review examines current knowledge of the pathophysiology of the organism. Diversity of C. jejuni isolates in genotypic and phenotypic characteristics now is recognized and clinically relevant examples are presented. Expected future directions are outlined.

Original language	English (US)
Pages (from-to)	1023-1033
Number of pages	11
Journal	Microbes and Infection
Volume	1
Issue number	12
DOIs	https://doi.org/10.1016/S1286-4579(99)80520-6
State	Published - Oct 1999
Externally published	Yes

All Science Journal Classification (ASJC) codes

Microbiology
Immunology
Infectious Diseases

Keywords

Bacterial toxins
Campylobacter
Emerging infections
Enteric diseases
Microbial pathogenesis

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10.1016/S1286-4579(99)80520-6

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abstract = "Campylobacter jejuni and closely related organisms are major cause of human bacterial enteritis. These infections can lead to extraintestinal disease and severe long-term complications. Of these, neurological damage, apparently due to the immune response of the host, is the most striking. This review examines current knowledge of the pathophysiology of the organism. Diversity of C. jejuni isolates in genotypic and phenotypic characteristics now is recognized and clinically relevant examples are presented. Expected future directions are outlined.",

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AU - Blaser, Martin J.

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AB - Campylobacter jejuni and closely related organisms are major cause of human bacterial enteritis. These infections can lead to extraintestinal disease and severe long-term complications. Of these, neurological damage, apparently due to the immune response of the host, is the most striking. This review examines current knowledge of the pathophysiology of the organism. Diversity of C. jejuni isolates in genotypic and phenotypic characteristics now is recognized and clinically relevant examples are presented. Expected future directions are outlined.

KW - Bacterial toxins

KW - Campylobacter

KW - Emerging infections

KW - Enteric diseases

KW - Microbial pathogenesis

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SN - 1286-4579

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ER -

Pathophysiology of Campylobacter jejuni infections of humans

Abstract

All Science Journal Classification (ASJC) codes

Keywords

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