Pathophysiology of Campylobacter jejuni infections of humans

Trudy M. Wassenaar, Martin J. Blaser

Research output: Contribution to journalReview articlepeer-review

169 Scopus citations


Campylobacter jejuni and closely related organisms are major cause of human bacterial enteritis. These infections can lead to extraintestinal disease and severe long-term complications. Of these, neurological damage, apparently due to the immune response of the host, is the most striking. This review examines current knowledge of the pathophysiology of the organism. Diversity of C. jejuni isolates in genotypic and phenotypic characteristics now is recognized and clinically relevant examples are presented. Expected future directions are outlined.

Original languageEnglish (US)
Pages (from-to)1023-1033
Number of pages11
JournalMicrobes and Infection
Issue number12
StatePublished - Oct 1999
Externally publishedYes

All Science Journal Classification (ASJC) codes

  • Microbiology
  • Immunology
  • Infectious Diseases


  • Bacterial toxins
  • Campylobacter
  • Emerging infections
  • Enteric diseases
  • Microbial pathogenesis


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