Patient compliance and its impact on treatment outcomes

Laura T. Pizzi, Joseph E. Biskupiak

Research output: Contribution to journalReview articlepeer-review

3 Scopus citations


Despite an abundance of literature that assesses medication compliance associated with specific diseases, its impact on patient outcomes remains poorly characterised, perhaps due to the complexity associated with its influence and measurement. Much of the previous research includes end-points that were reflective of the duration and pattern of medication use; the value of which is questionable. In fact, the accuracy of compliance data remains highly controversial due to the difficulties associated with its measurement. Monitoring, by itself, may result in minor improvements in medication compliance; monitoring that is coupled to a meaningful clinical outcome that patients can self-measure results in enhanced compliance. Disease management programmes frequently contain interventions to impact compliance. Disease management programme developers interested in positively affecting compliance should incorporate patient self-monitoring methods into their compliance interventions.

Original languageEnglish (US)
Pages (from-to)269-278
Number of pages10
JournalDisease Management and Health Outcomes
Issue number5
StatePublished - 1999

All Science Journal Classification (ASJC) codes

  • Leadership and Management
  • Nursing(all)
  • Health Policy


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