Patient-specific aortic valve blood flow simulations

Scott Kulp, Zhen Qian, Mani Vannan, Sarah Rinehart, Dimitris Metaxas

Research output: Chapter in Book/Report/Conference proceedingConference contribution

7 Scopus citations

Abstract

In this paper, we present a novel framework to simulate and visualize blood flow at high levels of detail through the aortic valve. We generate a 4D reconstruction of the aortic root using contrast-enhanced CT imagery, and attach it to a model of the left ventricle segmented from the Visible Human Project dataset. This full R-R animated model is then used as solid boundary conditions in a highly-accurate FDM Navier-Stokes fluid solver. We perform this simulation on both healthy and diseased aortic hearts, and then build visualizations of the velocity and vorticity fields produced by the simulator. In our quantitative analysis of the flow, we find significantly elevated vorticities in the diseased valve simulation. These results produce a view of the flow fields clearer than previous imaging techniques can provide.

Original languageEnglish (US)
Title of host publication2014 IEEE 11th International Symposium on Biomedical Imaging, ISBI 2014
PublisherInstitute of Electrical and Electronics Engineers Inc.
Pages939-942
Number of pages4
ISBN (Electronic)9781467319591
DOIs
StatePublished - Jul 29 2014
Event2014 IEEE 11th International Symposium on Biomedical Imaging, ISBI 2014 - Beijing, China
Duration: Apr 29 2014May 2 2014

Publication series

Name2014 IEEE 11th International Symposium on Biomedical Imaging, ISBI 2014

Other

Other2014 IEEE 11th International Symposium on Biomedical Imaging, ISBI 2014
Country/TerritoryChina
CityBeijing
Period4/29/145/2/14

All Science Journal Classification (ASJC) codes

  • Biomedical Engineering
  • Radiology Nuclear Medicine and imaging

Keywords

  • Aortic valve
  • Blood flow
  • CT

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