TY - GEN
T1 - Patient-specific modeling and visualization of blood flow through the heart
AU - Kulp, Scott
AU - Metaxas, Dimitris
AU - Qian, Zhen
AU - Voros, Szilard
AU - Axel, Leon
AU - Mihalef, Viorel
PY - 2011
Y1 - 2011
N2 - Many cardiovascular diseases, such as ischemia and arrhythmia, will cause abnormal motion of the myocardium, leading to a change of the blood flow pattern in the heart and an increased risk of the formation of thrombus. In this paper, we propose a new method to use high-resolution 4D CT data to model the complex moving boundaries of the heart walls, accurately simulate blood flow using the Navier-Stokes equations, and visualize the flow in order to view interactions between the heart walls and the fluid. We then visually and quantitatively compare the flow in a normal heart to that of a heart suffering from hypokinesis, and see how the diseased heart is at greater risk of blood clotting. In a clinical setting, these types of visualizations could prove to be invaluable, allowing doctors to more easily diagnose and prescribe treatments for certain conditions.
AB - Many cardiovascular diseases, such as ischemia and arrhythmia, will cause abnormal motion of the myocardium, leading to a change of the blood flow pattern in the heart and an increased risk of the formation of thrombus. In this paper, we propose a new method to use high-resolution 4D CT data to model the complex moving boundaries of the heart walls, accurately simulate blood flow using the Navier-Stokes equations, and visualize the flow in order to view interactions between the heart walls and the fluid. We then visually and quantitatively compare the flow in a normal heart to that of a heart suffering from hypokinesis, and see how the diseased heart is at greater risk of blood clotting. In a clinical setting, these types of visualizations could prove to be invaluable, allowing doctors to more easily diagnose and prescribe treatments for certain conditions.
KW - Blood flow
KW - CT
KW - cardiac
KW - hypokinesis
UR - http://www.scopus.com/inward/record.url?scp=80055048300&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=80055048300&partnerID=8YFLogxK
U2 - 10.1109/ISBI.2011.5872730
DO - 10.1109/ISBI.2011.5872730
M3 - Conference contribution
AN - SCOPUS:80055048300
SN - 9781424441280
T3 - Proceedings - International Symposium on Biomedical Imaging
SP - 1692
EP - 1697
BT - 2011 8th IEEE International Symposium on Biomedical Imaging
T2 - 2011 8th IEEE International Symposium on Biomedical Imaging: From Nano to Macro, ISBI'11
Y2 - 30 March 2011 through 2 April 2011
ER -