Pelvic neurectomy blocks oxytocin-facilitated sexual receptivity in rats

Kathleen M. Moody; Judith L. Steinman; Barry R. Komisaruk; Norman T. Adler

doi:10.1016/0031-9384(94)90343-3

Pelvic neurectomy blocks oxytocin-facilitated sexual receptivity in rats

Kathleen M. Moody, Judith L. Steinman, Barry R. Komisaruk, Norman T. Adler

Research output: Contribution to journal › Article › peer-review

26 Scopus citations

Abstract

The effect of bilateral pelvic, hypogastric, or pudendal neurectomy on oxytocin-induced facilitation of lordosis behavior was examined in ovariectomized, estrogen, and progesterone primed female rats. Oxytocin-induced facilitation of lordosis behavior was significantly decreased following bilateral pelvic, or combined bilateral pelvic and hypogastric neurectomy. Hypogastric only or pudendal only neurectomy had no effect on the facilitation of lordosis behavior after systemic administration of oxytocin. These results suggest that the integrity of the pelvic nerve is necessary and sufficient to mediate the stimulatory effects of systemically administered oxytocin on receptivity.

Original language	English (US)
Pages (from-to)	1057-1060
Number of pages	4
Journal	Physiology and Behavior
Volume	56
Issue number	5
DOIs	https://doi.org/10.1016/0031-9384(94)90343-3
State	Published - Nov 1994

All Science Journal Classification (ASJC) codes

Experimental and Cognitive Psychology
Behavioral Neuroscience

Keywords

Facilitated behavior
Hypogastric nerve
Lordosis
Oxytocin
Pelvic nerve
Pudendal nerve
Receptivity
Systemic

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10.1016/0031-9384(94)90343-3

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title = "Pelvic neurectomy blocks oxytocin-facilitated sexual receptivity in rats",

abstract = "The effect of bilateral pelvic, hypogastric, or pudendal neurectomy on oxytocin-induced facilitation of lordosis behavior was examined in ovariectomized, estrogen, and progesterone primed female rats. Oxytocin-induced facilitation of lordosis behavior was significantly decreased following bilateral pelvic, or combined bilateral pelvic and hypogastric neurectomy. Hypogastric only or pudendal only neurectomy had no effect on the facilitation of lordosis behavior after systemic administration of oxytocin. These results suggest that the integrity of the pelvic nerve is necessary and sufficient to mediate the stimulatory effects of systemically administered oxytocin on receptivity.",

keywords = "Facilitated behavior, Hypogastric nerve, Lordosis, Oxytocin, Pelvic nerve, Pudendal nerve, Receptivity, Systemic",

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AU - Moody, Kathleen M.

AU - Steinman, Judith L.

AU - Komisaruk, Barry R.

AU - Adler, Norman T.

PY - 1994/11

Y1 - 1994/11

N2 - The effect of bilateral pelvic, hypogastric, or pudendal neurectomy on oxytocin-induced facilitation of lordosis behavior was examined in ovariectomized, estrogen, and progesterone primed female rats. Oxytocin-induced facilitation of lordosis behavior was significantly decreased following bilateral pelvic, or combined bilateral pelvic and hypogastric neurectomy. Hypogastric only or pudendal only neurectomy had no effect on the facilitation of lordosis behavior after systemic administration of oxytocin. These results suggest that the integrity of the pelvic nerve is necessary and sufficient to mediate the stimulatory effects of systemically administered oxytocin on receptivity.

AB - The effect of bilateral pelvic, hypogastric, or pudendal neurectomy on oxytocin-induced facilitation of lordosis behavior was examined in ovariectomized, estrogen, and progesterone primed female rats. Oxytocin-induced facilitation of lordosis behavior was significantly decreased following bilateral pelvic, or combined bilateral pelvic and hypogastric neurectomy. Hypogastric only or pudendal only neurectomy had no effect on the facilitation of lordosis behavior after systemic administration of oxytocin. These results suggest that the integrity of the pelvic nerve is necessary and sufficient to mediate the stimulatory effects of systemically administered oxytocin on receptivity.

KW - Facilitated behavior

KW - Hypogastric nerve

KW - Lordosis

KW - Oxytocin

KW - Pelvic nerve

KW - Pudendal nerve

KW - Receptivity

KW - Systemic

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Pelvic neurectomy blocks oxytocin-facilitated sexual receptivity in rats

Abstract

All Science Journal Classification (ASJC) codes

Keywords

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