Perspectives on next steps in classification of oro-facial pain - Part 3: Biomarkers of chronic oro-facial pain - from research to clinic

W. Ceusters, C. Nasri-Heir, D. Alnaas, B. E. Cairns, A. Michelotti, R. Ohrbach

Research output: Contribution to journalReview articlepeer-review

10 Scopus citations

Abstract

Summary: The purpose of this study was to review the current status of biomarkers used in oro-facial pain conditions. Specifically, we critically appraise their relative strengths and weaknesses for assessing mechanisms associated with the oro-facial pain conditions and interpret that information in the light of their current value for use in diagnosis. In the third section, we explore biomarkers through the perspective of ontological realism. We discuss ontological problems of biomarkers as currently widely conceptualised and implemented. This leads to recommendations for research practice aimed to a better understanding of the potential contribution that biomarkers might make to oro-facial pain diagnosis and thereby fulfil our goal for an expanded multidimensional framework for oro-facial pain conditions that would include a third axis.

Original languageEnglish (US)
Pages (from-to)956-966
Number of pages11
JournalJournal of Oral Rehabilitation
Volume42
Issue number12
DOIs
StatePublished - Dec 1 2015

All Science Journal Classification (ASJC) codes

  • Dentistry(all)

Keywords

  • Biomarkers
  • Chronic oro-facial pain
  • Classification
  • Ontology
  • Pain
  • Temporomandibular disorders

Fingerprint

Dive into the research topics of 'Perspectives on next steps in classification of oro-facial pain - Part 3: Biomarkers of chronic oro-facial pain - from research to clinic'. Together they form a unique fingerprint.

Cite this