Picornaviruses of two different genera have similar structures

Ming Luo, Edward Arnold, John W. Erickson, Michael G. Rossmann, Ulrike Boege, Douglas G. Scraba

Research output: Contribution to journalArticle

1 Scopus citations


Crystals of Mengo virus were used to collect three-dimensional X-ray diffraction data to 7 Å resolution. A self-rotation function showed the precise orientation of the Mengo particles in the crystal unit cell. A cross-rotation function against similar data of cubic rhinovirus crystals showed a peak when the orientations of these two icosahedral viruses were superimposed. This demonstrates similarity of capsid construction between two picornaviruses of different taxonomic genera.

Original languageEnglish (US)
Pages (from-to)703-714
Number of pages12
JournalJournal of molecular biology
Issue number3
StatePublished - Dec 15 1984
Externally publishedYes

All Science Journal Classification (ASJC) codes

  • Structural Biology
  • Molecular Biology

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    Luo, M., Arnold, E., Erickson, J. W., Rossmann, M. G., Boege, U., & Scraba, D. G. (1984). Picornaviruses of two different genera have similar structures. Journal of molecular biology, 180(3), 703-714. https://doi.org/10.1016/0022-2836(84)90033-0