Pilot trial of speed-intensive gait training on balance and walking in people with multiple sclerosis

Herb I. Karpatkin, Allison Benson, Nolan Gardner, Naomi Leb, Nicole Ramos, Huiman Xu, Evan T. Cohen

Research output: Contribution to journalArticlepeer-review

2 Scopus citations


Background/aims Diminished walking speed and endurance is commonly experienced by individuals with multiple sclerosis. Speed-intensive gait training has led to improvements in walking speed and endurance in other neurological populations; however, its effect in persons with multiple sclerosis is unknown. This pilot study examined the feasibility, safety and efficacy of speed-intensive gait training in a sample of people with multiple sclerosis. Methods A total of eight participants (five women, median Expanded Disability Status Scale 3.5) underwent a 6-week, twice weekly speed-intensive gait training programme. Walking speed and endurance, balance and fatigue were measured pre- and post-intervention. Results Speed-intensive gait training was feasible, with excellent adherence and safety. It proved effective, with improvements in walking speed (P=0.05), walking endurance (P=0.036) and balance (P=0.041) without an increase in fatigue. conclusions The intermittent design of speed-intensive gait training may enable individuals with multiple sclerosis to achieve higher training volumes than traditional models. Although further study is warranted, rehabilitation clinicians should consider adding speed-intensive gait training as an intervention to improve walking and balance in this patient group.

Original languageEnglish (US)
Article number0059
JournalInternational Journal of Therapy and Rehabilitation
Issue number11
StatePublished - Nov 2 2020

All Science Journal Classification (ASJC) codes

  • Physical Therapy, Sports Therapy and Rehabilitation
  • Rehabilitation


  • Balance
  • Fatigue
  • Multiple sclerosis
  • Physiotherapy
  • Walking


Dive into the research topics of 'Pilot trial of speed-intensive gait training on balance and walking in people with multiple sclerosis'. Together they form a unique fingerprint.

Cite this