Platelet-rich plasma and its uses in foot and ankle surgery

John Koerner, Peter Abdelmessieh, Vikrant Azad, Karolynn Szczepanowski, Sheldon S. Lin, Michael Pinzur

Research output: Contribution to journalReview articlepeer-review

3 Scopus citations

Abstract

With advances in basic science, the use of biological adjuncts is currently being explored to supplement orthopedic surgery. Platelet-rich plasma is a clinical concept of autologous intraoperative concentration of serum plateletsto provide high levels of early critical growth factors for implantation into fracture, arthrodesis, or nonunion sites. The theoretical benefit of a biological adjunct like platelet-rich plasma has been to significantly enhance fusion rates. Platelet-rich plasma has been definedas a volume of plasma that has a platelet concentration above physiological levels, typically a 5-fold increase. Application of autologous platelet concentrate is a simple procedure with minimal morbidity, which is also inexpensive. Although an abundance of literature exists pertaining to dental applications, few data exist on orthopedic applications.

Original languageEnglish (US)
Pages (from-to)72-78
Number of pages7
JournalTechniques in Foot and Ankle Surgery
Volume7
Issue number2
DOIs
StatePublished - Jun 1 2008

All Science Journal Classification (ASJC) codes

  • Surgery
  • Orthopedics and Sports Medicine

Keywords

  • Bone healing
  • Fracture
  • Growth factor
  • Nonunion
  • Platelet-rich plasma

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