With advances in basic science, the use of biological adjuncts is currently being explored to supplement orthopedic surgery. Platelet-rich plasma is a clinical concept of autologous intraoperative concentration of serum plateletsto provide high levels of early critical growth factors for implantation into fracture, arthrodesis, or nonunion sites. The theoretical benefit of a biological adjunct like platelet-rich plasma has been to significantly enhance fusion rates. Platelet-rich plasma has been definedas a volume of plasma that has a platelet concentration above physiological levels, typically a 5-fold increase. Application of autologous platelet concentrate is a simple procedure with minimal morbidity, which is also inexpensive. Although an abundance of literature exists pertaining to dental applications, few data exist on orthopedic applications.
All Science Journal Classification (ASJC) codes
- Orthopedics and Sports Medicine
- Bone healing
- Growth factor
- Platelet-rich plasma