Abstract
The management of the liver transplant (OLT) candidate with portopulmonary hypertension (PPHTN) has dramatically changed in the past 3 years. Careful preoperative evaluation with functional characterization of right ventricular function plays a critical role. The pulmonary vascular response to epoprostenol infusion serves as a deciding factor for OLT candidacy. Careful perioperative attention to avoid right ventricular failure from acutely elevated pulmonary artery pressures or sudden increases in right ventricular preload is a key physiologic tenet of management. With increased surgical expertise, anesthetic sophistication, and availability of epoprostenol, PPHTN is no longer considered an absolute contraindication for OLT.
Original language | English (US) |
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Pages (from-to) | 1087-1093 |
Number of pages | 7 |
Journal | Transplantation |
Volume | 67 |
Issue number | 8 |
DOIs | |
State | Published - Apr 27 1999 |
Externally published | Yes |
All Science Journal Classification (ASJC) codes
- Transplantation