Postrepolarization refractoriness in the ventricular muscle

V. Kowtha, J. K.J. Li

Research output: Contribution to conferencePaperpeer-review

1 Scopus citations


The authors extend an experimental model to a two-dimensional analysis of postrepolarization refractoriness (PRR) and ventricular arrhythmias. The rectifying potassium channel in the plateau phase of the model plays a major role in the near-synchronous repolarization in the normal tissue. With changes in the time constant of inactivation of inward currents and with the concentration changes in calcium and potassium ion, the action potential duration can be seen to be affected adversely. This, coupled with the poor cellular communication observed, affects the slow recovery of subthreshold currents, leading to PRR.

Original languageEnglish (US)
Number of pages2
StatePublished - 1989
EventProceedings of the Fifteenth Annual Northeast Bioengineering Conference - Boston, MA, USA
Duration: Mar 27 1989Mar 28 1989


OtherProceedings of the Fifteenth Annual Northeast Bioengineering Conference
CityBoston, MA, USA

All Science Journal Classification (ASJC) codes

  • Bioengineering


Dive into the research topics of 'Postrepolarization refractoriness in the ventricular muscle'. Together they form a unique fingerprint.

Cite this