Posttranslational modifications of keratins and their associated proteins as therapeutic targets in keratin diseases

Keyphrases

• Therapeutic Target 100%
• Post-translational Modification 100%
• Keratin 100%
• Associated Proteins 100%
• Keratin mutations 40%
• Keratinopathies 40%
• High-throughput Screening 20%
• Drug Use 20%
• Epithelium 20%
• Skin Diseases 20%
• Human Disease 20%
• Phosphorylation 20%
• Drug Target 20%
• Human Use 20%
• Multiple Signaling Pathways 20%
• Mechanical Stress 20%
• Resilience 20%
• Acetylation 20%
• Disease-related 20%
• Repurposing 20%
• Physical Stress 20%
• Cell Integrity 20%
• Drug Mixtures 20%
• Monoallelic 20%
• Epidermolysis Bullosa 20%
• Non-mechanical 20%
• Keratin Cytoskeleton 20%
• Low-side 20%
• Pachyonychia Congenita 20%

Pharmacology, Toxicology and Pharmaceutical Science

• Keratin 100%
• Diseases 100%
• Side Effect 12%
• High-Throughput Screening 12%
• Drug Mixture 12%
• Epidermolysis Bullosa Simplex 12%
• Congenital Pachyonychia 12%