Potential Application of Tea Polyphenols to the Prevention of COVID-19 Infection: Based on the Gut-Lung Axis

Lei Xu; Chi Tang Ho; Yanan Liu; Zufang Wu; Xin Zhang

doi:10.3389/fnut.2022.899842

Potential Application of Tea Polyphenols to the Prevention of COVID-19 Infection: Based on the Gut-Lung Axis

Lei Xu, Chi Tang Ho, Yanan Liu, Zufang Wu, Xin Zhang

Research output: Contribution to journal › Review article › peer-review

6 Scopus citations

Abstract

Coronavirus disease 2019 (COVID-19) disrupts the intestinal micro-ecological balance, and patients often develop the intestinal disease. The gut is the largest immune organ in the human body; intestinal microbes can affect the immune function of the lungs through the gut-lung axis. It has been reported that tea polyphenols (TPs) have antiviral and prebiotic activity. In this review, we discussed TPs reduced lung-related diseases through gut-lung axis by inhibiting dysbiosis. In addition, we also highlighted the preventive and therapeutic effects of TPs on COVID-19 complications, further demonstrating the importance of research on TPs for the prevention and treatment of COVID-19 in humans. Based on this understanding, we recommend using TPs to regulate the gut microbiota to prevent or alleviate COVID-19 through the gut-lung axis.

Original language	English (US)
Article number	899842
Journal	Frontiers in Nutrition
Volume	9
DOIs	https://doi.org/10.3389/fnut.2022.899842
State	Published - Apr 14 2022
Externally published	Yes

All Science Journal Classification (ASJC) codes

Food Science
Endocrinology, Diabetes and Metabolism
Nutrition and Dietetics

Keywords

antiviral
COVID-19
gut microbiota
gut-lung axis
tea polyphenols

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10.3389/fnut.2022.899842

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@article{e8b88cb01565456c99ae6f956d829708,

title = "Potential Application of Tea Polyphenols to the Prevention of COVID-19 Infection: Based on the Gut-Lung Axis",

abstract = "Coronavirus disease 2019 (COVID-19) disrupts the intestinal micro-ecological balance, and patients often develop the intestinal disease. The gut is the largest immune organ in the human body; intestinal microbes can affect the immune function of the lungs through the gut-lung axis. It has been reported that tea polyphenols (TPs) have antiviral and prebiotic activity. In this review, we discussed TPs reduced lung-related diseases through gut-lung axis by inhibiting dysbiosis. In addition, we also highlighted the preventive and therapeutic effects of TPs on COVID-19 complications, further demonstrating the importance of research on TPs for the prevention and treatment of COVID-19 in humans. Based on this understanding, we recommend using TPs to regulate the gut microbiota to prevent or alleviate COVID-19 through the gut-lung axis.",

keywords = "antiviral, COVID-19, gut microbiota, gut-lung axis, tea polyphenols",

author = "Lei Xu and Ho, {Chi Tang} and Yanan Liu and Zufang Wu and Xin Zhang",

note = "Funding Information: This work was sponsored by Zhejiang Provincial Key Research and Development Program (2020C02037) and the Ningbo Natural Science Foundation (2021J107). Publisher Copyright: Copyright {\textcopyright} 2022 Xu, Ho, Liu, Wu and Zhang.",

year = "2022",

month = apr,

day = "14",

doi = "10.3389/fnut.2022.899842",

language = "English (US)",

volume = "9",

journal = "Frontiers in Nutrition",

issn = "2296-861X",

publisher = "Frontiers Media S. A.",

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T1 - Potential Application of Tea Polyphenols to the Prevention of COVID-19 Infection

T2 - Based on the Gut-Lung Axis

AU - Xu, Lei

AU - Ho, Chi Tang

AU - Liu, Yanan

AU - Wu, Zufang

AU - Zhang, Xin

N1 - Funding Information: This work was sponsored by Zhejiang Provincial Key Research and Development Program (2020C02037) and the Ningbo Natural Science Foundation (2021J107). Publisher Copyright: Copyright © 2022 Xu, Ho, Liu, Wu and Zhang.

PY - 2022/4/14

Y1 - 2022/4/14

N2 - Coronavirus disease 2019 (COVID-19) disrupts the intestinal micro-ecological balance, and patients often develop the intestinal disease. The gut is the largest immune organ in the human body; intestinal microbes can affect the immune function of the lungs through the gut-lung axis. It has been reported that tea polyphenols (TPs) have antiviral and prebiotic activity. In this review, we discussed TPs reduced lung-related diseases through gut-lung axis by inhibiting dysbiosis. In addition, we also highlighted the preventive and therapeutic effects of TPs on COVID-19 complications, further demonstrating the importance of research on TPs for the prevention and treatment of COVID-19 in humans. Based on this understanding, we recommend using TPs to regulate the gut microbiota to prevent or alleviate COVID-19 through the gut-lung axis.

AB - Coronavirus disease 2019 (COVID-19) disrupts the intestinal micro-ecological balance, and patients often develop the intestinal disease. The gut is the largest immune organ in the human body; intestinal microbes can affect the immune function of the lungs through the gut-lung axis. It has been reported that tea polyphenols (TPs) have antiviral and prebiotic activity. In this review, we discussed TPs reduced lung-related diseases through gut-lung axis by inhibiting dysbiosis. In addition, we also highlighted the preventive and therapeutic effects of TPs on COVID-19 complications, further demonstrating the importance of research on TPs for the prevention and treatment of COVID-19 in humans. Based on this understanding, we recommend using TPs to regulate the gut microbiota to prevent or alleviate COVID-19 through the gut-lung axis.

KW - antiviral

KW - COVID-19

KW - gut microbiota

KW - gut-lung axis

KW - tea polyphenols

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DO - 10.3389/fnut.2022.899842

M3 - Review article

AN - SCOPUS:85133814912

SN - 2296-861X

VL - 9

JO - Frontiers in Nutrition

JF - Frontiers in Nutrition

M1 - 899842

ER -

Potential Application of Tea Polyphenols to the Prevention of COVID-19 Infection: Based on the Gut-Lung Axis

Abstract

All Science Journal Classification (ASJC) codes

Keywords

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