Practical considerations for the dosing and adjustment of continuous renal replacement therapy in the intensive care unit

Samuel M. Galvagno, Caron M. Hong, Matthew E. Lissauer, Andrew K. Baker, Sarah B. Murthi, Daniel L. Herr, Deborah M. Stein

Research output: Contribution to journalArticle

7 Scopus citations

Abstract

Familiarity with the initiation, dosing, adjustment, and termination of continuous renal replacement therapy (CRRT) is a core skill for contemporary intensivists. Guidelines for how to administer CRRT in the intensive care unit are not well documented. The purpose of this review is to discuss the modalities, terminology, and components of CRRT, with an emphasis on the practical aspects of dosing, adjustments, and termination. Management of electrolyte and acid-base derangements commonly encountered with acute renal failure is emphasized. Knowledge regarding the practical aspects of managing CRRT in the intensive care unit is a prerequisite for achieving desired physiological end points.

Original languageEnglish (US)
Pages (from-to)1019-1026
Number of pages8
JournalJournal of Critical Care
Volume28
Issue number6
DOIs
StatePublished - Dec 1 2013
Externally publishedYes

All Science Journal Classification (ASJC) codes

  • Critical Care and Intensive Care Medicine

Keywords

  • Continuous renal replacement therapy
  • Dosing
  • Intensive care unit

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